In Vitro Hypoglycemic Activity of Ethnopharmacological Important Plant of Chhattisgarh Plummbago Zelynica (Chitrak) against 3T3 - L1 diabetes Cell Lines

Plumbago zeylanica is a native plant of India belonging to the family Pumbago zeylanica. The aim of the present research was to evaluate the cytotoxicity and glucose uptake activity of methanolic extract of roots of Plumbago zeylanica using 3T3 cell lines. The results were found that the extracts showed cytotoxicity and the methanolic extract showed better glucose uptake potential. The results were compared with Plumbago zeylanica extract and rosiglitazone, which was used as the standard anti diabetic drugs. Rosiglitazone (100 μg/ml) and Plumbago zeylanica (500 μg/ml) enhance the glucose uptake over control.