Journal of the Indian Society of Toxicology
  • Year: 2005
  • Volume: 1
  • Issue: 2

Metformin Overdose: A Case Report

  • Author:
  • O Dogru, R Koken1, A Bukulmez1, Yurumez2, Y Yavuz2, F Ovali3
  • Total Page Count: 3
  • Page Number: 41 to 43

1Dept of Paediatrics

2Dept of Emergency Medicine

3Dept of Paediatrics, Afyon Kocatepe University, Faculty of Medicine, Afyon, Turkey

*(Corresponding author), Dept of Paediatrics

Abstract

Metformin is widely used in the treatment of type 2 diabetes. Overdose with this drug in children may cause profound, wide anion-gap metabolic acidosis and may be potentially lethal. After correction of circulation deficits, bicarbonate replacement may be sufficient for the treatment of acidosis, and there may be no need for haemodyalisis. A case of a teenager is reported in this paper who ingested one of the largest amounts of metformin reported in the literature in a suicide attempt.

Keywords

metformin, paediatric, lactic acidosis