1Department of Forensic Medicine and Toxicology, JIPMER, Karaikal, Pondicherry
2Department of Forensic Medicine and Toxicology, Aarupadai Veedu Medical Collage, Pondicherry
3Department of Forensic Medicine and Toxicology, JIPMER, Pondicherry
*Corresponding author: Email: drgerardfm@gmail.com
Online published on 16 February, 2018.
Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI), used in the treatment of depression. Venlafaxine is associated with high risk of suicidal ideation and complete suicide. A 32 year old female, who was treated with venlafaxine, died following ingestion of large dose of venlafaxine and escitalopram. Cadiotoxicity and neurotoxicity following ingestion of venlafaxine is known, however post-mortem studies are very few in literature. This case highlights the toxicity of venlafaxine and escitalopram with its histopathological findings of tissue and various drug interactions.
Venlafaxine, escitalopram, suicide, cardiotoxicity, hepatic necrosis
