1Department of General Medicine, Govt. Medical College, Srinagar
*Corresponding author: Muzzafer Mohammad Mir Department of General Medicine, Govt. Medical College, Srinagar.; E-mail: drmuzzafer@yahoo.co.in: Tel.: 7006250472
Online published on 25 October, 2019.
In Asia around 50% poisoning are due to organophosphorus (OP) poisoning. The estimated mortality from Organophosphates ingestion ranges from 10% to 20%.
The present study was undertaken to study the glycemic changes in acute organophosphorus (anticholinesterase) poisoning and its relationship with severity, morbidity and mortality.
This prospective observational study was conducted in Government Medical College, Srinagar; Jammu Kashmir; India. Two hundred six patients with organophosphorus poisoning were studied.
In this study, the mortality was 10.2% (21 deaths in 206 patients), and ventilation was required in 29 (14.07%) patients. In patients who expired, glycosuria was found in 76.2% and blood glucose levels were 216±61 mg/dl, as compared to patients who survived in whom glycosuria was found in 9.2% and blood glucose levels were 136±88 mg/dl(P <0.005).
Glycemic changes (hyperglycemia and glycosuria) are good markers for predicting morbidity and also assessing need for ventilator support.
Glycemia, organophosphorus, glycosuria, blood glucose, hyperglycemia
