Journal of the Indian Society of Toxicology
  • Year: 2006
  • Volume: 2
  • Issue: 1

*Toxic Effects of Alcohol on Brain- An Overview

  • Author:
  • Sukhes Mukherjee, Subir Kumar Das, DM Vasudevan
  • Total Page Count: 1
  • Page Number: 23 to 23

Department of Biochemistry, Amrita Institute of Medical Sciences, Cochin 682026

*Winner of Best Paper Award in the category of Clinical Toxicology

Abstract

Multiple factors can influence the brain as a consequence of alcohol consumption. Alcoholism-related brain damage may be influenced by an individual's age, gender, drinking history, and nutrition, as well as by the vulnerability of specific areas of brain. Degeneration of neuronal cells is associated with alcohol pathology. One of the proposed mechanisms of alcohol-induced brain damage is the effect of increased oxidative stress through the generation of ROS, or the reduction of antioxidant levels, causing damage to mitochondria and altering the functions of glial cells.