Poison Control Training and Research Centre, Rajiv Gandhi Govt General Hospital, Chennai, 600003.
*Author for correspondence: Email: vijipg@hotmail.com
Online published on 21 June, 2012.
A case of acute dapsone poisoning in a 21 year-old female is being reported. Dapsone is well known for inducing serious methaemoglobinaemia and haemolysis in overdose situations. Estimating the methaemoglobin (MetHb) concentration in the blood is critical for effective management. Quantification of MetHb by spectrophotometer is generally advocated along with complete haematological and liver function investigations.
In this paper, we highlight the importance of quantifying MetHb by spectrophotometer, which is very simple, and demonstrates high sensitivity.
Dapsone overdose, Methaemoglobin (MetHb), Spectrophotometry, Liver function tests
