Journal of Medical Erudite
  • Year: 2015
  • Volume: 3
  • Issue: 1

Biochemical Profile in Clinically Diagnosed Patients of Glomerular Diseases with Edema in North Bihar

  • Author:
  • Pankaj Kumar Keshri1, S. Ahmad2, Santosh Kumar3, Jhilmil4, H.N. Jha5, Jyoti Priya6
  • Total Page Count: 9
  • Page Number: 55 to 63

1Assistant Professor, Department of Physiology, Pacific Institute of Medical Sciences, Udaipur, Rajasthan

2Professor, Department of Physiology, Darbhanga Medical College, Laheriasarai, Bihar

3Assistant Professor, Department of Medicine, SKBS Medical College & Research Centre, Vadodara, Gujrat

4Senior Resident, IGIMS, Patna, Bihar

5Professor & Head, Department of Physiology, Darbhanga Medical College, Laheriasarai, Bihar

6Assistant Professor, Department of Physiology, Vardman Institute of Medical Sciences, Pawapuri

Online published on 30 December, 2015.

Abstract

Kidney plays very importantrole in maintaining homeostasis, being functional unit of kidney, nephron is responsible for this. In certain diseases such as nephrotic and nephritic syndromes, renal involvement leads to edema. Edema can occur either due to sodium retention or hypoalbuminemia. The presentation of glomerular disease and the biochemical profile differs with region, race and also has shown change with changing times.

We investigated the biochemical profile in patients of glomerular diseases having edema in north Bihar region and also explored the role of serum albumin in edema genesis.

In our study, we recruited the diagnosed patients of nephrotic and nephritic syndrome of either gender in the age group of 03–30 years presenting with edema. They underwent blood investigations including blood urea, serum creatinine, serum cholesterol, serum albumin, erythrocyte sedimentation rate, total leukocyte count. Systolic and diastolic blood pressure was also measured in all patients.

Serum albumin level isinversely proportional to edema, but more consistently in patient of nephrotic syndrome rather than nephritic syndrome.

Keywords

Nephrotic syndrome, Nephritic syndrome, Edema