Hepatitis B and C are the diseases that are mostly transmitted by blood transfusion. This has serious complications like chronic hepatitis and cirrhosis and many times make the patient a lifelong carrier of the disease. This study is a retrospective study of eight years from January 2009 to December 2016 in which blood bank data was collected. As per the recommendations of the Food and Drug Administration, all the necessary screening investigations were done on the blood samples of blood donors i.e. Voluntary and replacement. These included detection of HIV I & II, Hepatitis B surface antigen, Hepatitis C, Malaria and syphilis. Hepatitis B detection was done by ELISA and strip method. In the above duration, 36, 415 donors were bled in the blood bank. Out of this, voluntary donors were only 675 1.85%) and remaining 35, 740 (98.14%) were replacement donors. Hepatitis B marker was analyzed and corresponding P value was calculated for each group of donors. Seropositivity for Hepatitis B marker was found in the replacement donors only, while no cases were found in voluntary donors.
HBsAg, Blood donors, Retrospective study, seropositivity