The HPV connection-correlation of oral papillomas in husband and wife

Literature analysis confirms the link between Human Papilloma Virus (HPV) and benign lesions of the oral cavity such as papillomas, condilomas and oral warts. Factors that contribute to increased HPV prevalence in the oral cavity are-reduction in host immune response for the virus, having more than one sexual partner and practice of oral sex. HPV diagnosis in the oral mucosa may be done by clinical examination of the lesion, family history, cytology and biopsy, however molecular biology allows detection of HPV DNA in cell, Polymerase Chain Reaction (PCR) being the most sensitive method for detection.

We report two cases of HPV linked squamous papilloma in husband and wife on the same unusual site in the oral cavity (hard palate), contemplating saliva to be a possible mode of transmission as the patients had no genital lesions with emphasis on diagnostic methods, treatment, recurrence and complications of such lesions.