Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology
  • Year: 2018
  • Volume: 4
  • Issue: 2

Basement membrane in health and disease-an enigma to histopathologist

  • Author:
  • Vijaykumar Biradar1,, Namita Shrivastav2, Priya Shree3, Rakhee Sinha4, Akhilanand Chaurasia5
  • Total Page Count: 6
  • Page Number: 100 to 105

1Reader, Dept. of Oral Pathology, Vananchal Dental College & Hospital, Garhwa, Jharkhand

2Senior Lecturer, Dept. of Oral Pathology, Vananchal Dental College & Hospital, Garhwa, Jharkhand

3Senior Lecturer, Dept. of Oral Pathology, Vananchal Dental College & Hospital, Garhwa, Jharkhand

4Senior Lecturer, Dept. of Oral Pathology, Vananchal Dental College & Hospital, Garhwa, Jharkhand

5Associate Professor, Dept. of Oral Medicine & Radiology, King's George Medical University, Lucknow, Uttar Pradesh, India

*Corresponding Author: Email: drvijay06_biradar@yahoo.com

Online published on 3 January, 2019.

Abstract

Basement membrane is known to play a role in the pathogenesis of inflammatory, tumor invasion, metastases and autoimmune diseases. A basement membrane (BM) is a thick sheet of extracellular matrix molecules, upon which epithelial cells attach and form a boundary between epithelium and the connective tissue. It also provides structural support for epithelial, mesothelial, and endothelial cells and surrounds adipocytes, muscles and Schwann cells. This literature review describes terminologies, histology, ultrastructure, molecular aspects, functions and histochemical studies of basement membrane in health and disease.

Keywords

Basement membrane, Extracellular matrix, Health, Disease