Thyrotoxic hypokalemic periodic paralysis (THPP) A case report and review of literature

Thyrotoxic Hypokalemic Periodic Paralysis (THPP) is one form of Periodic Paralysis, a rare group of disorders that can cause sudden onset of weakness. A case of a 29 year old male is presented here. The patient presented with sudden onset paralysis of his extremities. Laboratory evaluation revealed a markedly low potassium level. The patient's paralysis resolved upon repletion of his low potassium and he was discharged with no neurologic deficits. An association with thyroid disease is well established and further workup revealed Grave's disease in this patient. Although rare, Periodic Paralysis must differentiate from other causes of weakness and paralysis so that the proper treatment can be initiated quickly.