1 Dept of Medicine, School of Medical Sciences & Research, Sharda University, Greater Noida.
2 Dept of Oral Pathology & Microbiology, School of Dental Sciences, Sharda University, Greater Noida.
3 Medical Oncology, BMCHRC Hospital, Jaipur.
Cherubism is a rare, hereditary, non-neoplastic bone disease characterized by clinically evident bilateral, painless enlargement of jaws that is said to give the patient a cherubic appearance. It is a genetically transmitted in an autosomal dominant fashion and gene coding for SH3 binding protein 2(SH3BP2) may be involved.It is a disorder of age, related to bone remodeling, mostly limited to maxilla and the mandible, with loss of bone in the jaws and its replacement with large amounts of fibrous tissue.
Cherubism, Bilateral involvement, Self-limiting, Bone disease
