Microbial Genomics: What in store for Dentistry?

Information from the Human Genome Project (HGP) and the integration of information from related areas of study and technology will dramatically change health care for the craniofacial complex. The enormous diversity of culturable bacteria within the oral microbial community coupled with experimental accessibility renders the human oral cavity a valuable model to investigate genome-genome interactions. Hence a review was conducted with the aim to access the genomics of oral micro biota and its application in practice as well as the role of proteomics along with the microbial genomics. A bullion search showed around 300 articles. Integration of information from the human genome, comparative and microbial genomics, proteomics, bioinformatics, as well as related technologies will provide the basis for proactive prevention, intervention as well as novel and more efficient treatment approaches. Oral health care practitioners will increasingly require knowledge of human genetics and the application of new molecular based diagnostic and therapeutic technologies.