A Chronic Blistering Disease, Pemphigus Vulgaris

Pemphigus vulgaris (PV) is a chronic autoimmune mucocutaneous disease of skin and mucous membrane. It is characterized by impaired ce CC adhesion within the epidermis leading to the formation of intraepidermal bullae. The exact cause of the development of antibodies against the bodies owns tissues are unknown. Biopsy of perilesional tissue, with histological and immunostaining examinations, is essential to the diagnosis. As the oral mucosa is often the first site to be affected by the disease, the dentist should be able to recognize the early oral manifestations. Here, we report a case of pemphigus vulgaris which was diagnosed by the primary lesions of the oral mucosa. The present case report highlights need of a deductive analytical workout for diagnosing these lesions with a fact as many other disease entities pose a resemblance to pemphigus. Also timely management and achieving remission is the mainstay in controlling this dreaded disease.