Department of Oral Medicine and Radiology, Pacific Dental College, Udaipur, Rajasthan
*Address for Correspondence: Dr Revant Chole, Oral Medicine and Radiology, Faculty of Dental Sciences, Pacific University, Udaipur, Rajasthan Contact number: +919993665965. Email ID: drchole@rediffmail.com
Online published on 7 December, 2013.
The aim of this study was to evaluate the efficacy of spirulina in patients with oral submucous fibrosis
Fifty two patients with oral submucous fibrosis were randomly divided into 3 groups. Patients of group A (n = 17) received 16 mg of lycopene along with topical triamcinolone acetonide 0.1% (Cap Lycored + Ointment Kenacort), and those of group B (n = 16) were given a capsule spirulina 500 mg three times daily, and those of group C (n = 19) were given Spirulina + Triamcinolone acetonide 0.1%. Clinical follow up and review of all the patients was carried out at 15 days intervals for the whole trial period of 3 months.
Group A showed 65% increase in mouth opening, group B showed 82% increase in mouth opening and Group C showed 86% increase in mouth opening. Blanching of oral mucosa was decreased by 76% in group A, 85% in group B and 87% in group C. Burning sensation of oral mucosa was decreased by 68% in group A, 82% in group B and 90% in group C. Painful oral ulcerations were reduced by 68% in group A, 90% in group B and 93% in group C (Z > 1.96, P < 0.05). No reportable complications or side effects were recorded from any of the patients included in the study.
Spirulina is a safe and reliable modality in the management of oral submucous fibrosis.
oral submucous fibrosis, spirulina, lycopene, corticosteroid, triamcinolone acetonide
