Department of Conservative Dentistry and Endodontics, M.A. Rangoonwala College of Dental Sciences and Research Center, Pune
*Corresponding Address: Dr. Meheriar A Chopra Pg Student Department of Conservative Dentistry & Endodontics M.A. Rangoonwala College of Dental Sciences and Research Center, Pune.
Online published on 25 June, 2012.
The purpose of this cross-sectional study was to evaluate the relation between naturally occurring salivary IgA levels and dental caries susceptibility. 63 healthy individuals (age 20–55 yrs) were screened for the number of decayed, missing, and filled teeth (DMFT) and classified into three groups, Caries Free (CF) (DMFT=0), Low Caries Susceptibility (LCS) (DMFT=1–3), and High Caries Susceptibility (HCS) (DMFT >3). Whole un-stimulated saliva was collected in sterile cylindrical containers, processed and stored at sub 0 temp until assayed for salivary IgA by ELISA. GM: geometric mean of sIgA levels in ng/ml; significance at p>0.001.
The GM of CF(n=14), LCS(n=12) and HCS(n=37) cohort was 704.913, 458.351 and 359.466 respectively.
The CF group showed higher sIgA levels, compared to LCS and HCS group providing evidence to correlation between sIgA levels and caries susceptibility.
Salivary, Immunoglobulins
