1Professor, Dept of oral pathology and microbiology, Patna Dental College and Hospital
2Senior Lecturer, Dept of Oral Surgery, Azamgarh Dental Col, Azamgarh, U.P
3PG Student, Dept of Oral Pathology and Microbiology, U.P Dental College, Lucknow, UP
4Sr. Lecturer, Dept of Oral Pathology and Microbiology, Career Postgraduate Institute of Dental Sciences and Hospital
5PhD Srf, C.D.R.I, Lucknow
6PG student, Dept of Oral Pathology and Microbiology, Career Postgraduate Institute of Dental Sciences and Hospital
*Corresponding Author: Dr Akhtar Riaz, Sr. Lect, Career Postgraduate of Dental Sciences & Hospital, Lucknow, U.P.
Online published on 29 April, 2013.
Cancer is a malignant disease caused by damage of genes that control growth and division of cells and it is complex as it entails multiple cellular physiologic systems such as cell signalling and apoptosis it is being missed at its earliest stages because of detection methods that are not directed at cellular changes of carcinogenesis.
Non specific systemic distribution, inadequate drug concentrations reaching tumor, inability to monitor therapeutic responses continue to plague the area of clinical oncology. Nanotechnology has the potential to offer solution to these current obstacles in cancer therapy because of its unique size (1100nm) and large surface to volume ratios. The versatility of the nanotechnology platform could allow cellular tracking using single or multimodal imaging modalities.
Nanoparticles are being used to detect biomarkers which may help researchers with molecular imaging of malignant lesions and allow physicians to see cells and molecules undetectable through conventional imaging.
Additionally photo luminescent Nanoparticles may allow oncologists to discriminate cancerous and healthy cells. Investigations suggest that therapeutic Nanoparticles can improve patient care and quality of life by reducing off-target toxicities by more selectively directing drug molecules to intercellular targets of cancer cells.
Nano, Nano technology and cancer
