1, Dept. of Oral Medicine, Diagnosis and Maxillofacial Radiology, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab (India)
2Sr. Lecturer, Dept of Pedodontics, Eklavya Dental College, Kotputli
*Address For Correspondance: Dr. Sahil Jindal, Senior Lecturer, Dept. of Pedodontics and Preventive dentistry, Eklavya Dental College, Kotputli, Rajasthan (India)
Online published on 19 August, 2014.
Stevens-Johnson syndrome (SJS) is a mucocutaneous disorder induced by an immune complex mediated hypersensitivity reaction with widespread erythematous, cutaneous macules, severe mucosal erosions or atypical targets nearly half of cases are caused by a reaction to drugs or appear during viral infections and malignancies. A very few cases are caused by a bacterial infection (Streptococcus) or Mycoplasma pneumoniae. We report a case of a 25 year old female patient diagnosed as Stevens-Johnson syndrome induced by the overdosage of outdated acetaminophen who was systemically treated with corticosteroids along with supportive therapy successfully over a period of 20 days in hospital care. Successful management entails the early identification and withdrawal of the offending drug or possible drug(s), transfer to a specialized centre and supportive care employing intensive multidisciplinary approach in a hospital.
Stevens-Johnson syndrome, adverse drug reaction, symptoms, management
