1Senior Lecturer, Dept of oral medicine and radiology, Mamata Dental College and Hospital, Khammam, Andhra Pradesh, India
2Professor & Head, Dept of oral medicine and radiology, Mamata Dental College and Hospital, Khammam, Andhra Pradesh, India
3Professor & Head, Dept of oral medicine and radiology, Sri Sai College Of Dental Surgery, Vikarabad, Andhra Pradesh, India
4Post Graduate Student, Dept of oral medicine and radiology, Sri Sai College Of Dental Surgery, Vikarabad, Andhra Pradesh, India
5Senior Lecturer, Dept of oral medicine and radiology, H K D E Trust's Dental College and Hospital, Humnabad, India
*Address For Correspondance: Dr. Kotya Naik. Maloth, Senior Lecturer, Department of Oral Medicine and Radiology, Mamata Dental College and Hospital, Giriprasad Nagar Khammam, Andhra Pradesh, India. Mobile: 91-9885617131. Email: dr.kotyanaik.maloth@gmail.com
Online published on 19 August, 2014.
Stevens-Johnson syndrome (SJS) is a mucocutaneous disorder induced by an immune complex mediated hypersensitivity reaction with widespread erythematous, cutaneous macules, severe mucosal erosions or atypical targets nearly half of cases are caused by a reaction to drugs or appear during viral infections and malignancies. A very few cases are caused by a bacterial infection (Streptococcus) or Mycoplasma pneumoniae. We report a case of a 25 year old female patient diagnosed as Stevens-Johnson syndrome induced by the overdosage of outdated acetaminophen who was systemically treated with corticosteroids along with supportive therapy successfully over a period of 20 days in hospital care. Successful management entails the early identification and withdrawal of the offending drug or possible drug(s), transfer to a specialized centre and supportive care employing intensive multidisciplinary approach in a hospital.
Stevens-Johnson syndrome, adverse drug reaction, symptoms, management
