Journal of PEARLDENT
  • Year: 2015
  • Volume: 6
  • Issue: 3

Comparative evaluation of efficacy of topical 1% clotrimazole and topical 1% chlorhexidine digluconate in management of denture stomatitis patients

  • Author:
  • S. Kuchekar Kiran1, Zope Sameer2, Suragimath Girish3, Abbayya Keshava4, Varma Siddhartha5, Kale Vishwajeet6, S.R. Ashwini Rani7
  • Total Page Count: 5
  • Page Number: 17 to 21

1Final year B.D.S., Department of Periodontology, School Of Dental Sciences, Krishna Institute of Medical Sciences Deemed University, Karad, Satara (District), Maharashtra (State), India

2Senior Lecturer, Department of Periodontology, School Of Dental Sciences, Krishna Institute of Medical Sciences Deemed University, Karad, Satara (District), Maharashtra (State), India

3Professor And Head, Department of Periodontology, School Of Dental Sciences, Krishna Institute of Medical Sciences Deemed University, Karad, Satara (District), Maharashtra (State), India

4Reader, Department of Periodontology, School Of Dental Sciences, Krishna Institute of Medical Sciences Deemed University, Karad, Satara (District), Maharashtra (State), India

5Reader, Department of Periodontology, School Of Dental Sciences, Krishna Institute of Medical Sciences Deemed University, Karad, Satara (District), Maharashtra (State), India

6Senior Lecturer, Department of Periodontology, School Of Dental Sciences, Krishna Institute of Medical Sciences Deemed University, Karad, Satara (District), Maharashtra (State), India

7Senior Lecturer, Department of Oral Medicine and Radiology, School Of Dental Sciences, Krishna Institute of Medical Sciences Deemed University, Karad, Satara (District), Maharashtra (State), India

Online published on 23 November, 2015.

Abstract

Candida-associated denture stomatitis is characterized by generalized inflammation of the palatal mucosa covered by a denture. The aim of this study was to evaluate effectiveness of topical 1% clotrimazole and 1% chlorhexidine digluconate in management of denture stomatitis patients.

This study was a randomised clinical trial conducted on 30 denture stomatitis patients in the age range of 40–70 years who were divided into two groups. Patients in Group 1 (n=15) were treated with topical clotrimazole (1% paste, thrice daily application) whereas those in Group 2 (n=15) were treated with topical chlorhexidine digluconate (1% gel, thrice daily application). The clinical efficacy of treatment was evaluated by recording the mean scores of signs and symptoms and clinical response to treatment of denture stomatitis after 21 days.

At the follow up visit, patients in Group 1 showed; significant reduction in soreness and inflammation while group 2 showed significant reductions in soreness only. Clinical response to treatment in group 1 was graded as 53.3% cure, 33.3% improvement and 13.3% failure, whereas in Group 2 it was 26.6% cure, 46.6% improvement 26.6% failure. On intergroup comparison, there was no statistical significant difference observed between both the treatment groups.

Considering the effectiveness of treatment modalities used in this study, 1% clotrimazole application was found to be relatively more effective than 1% chlorhexidine application in controlling signs and symptoms associated with denture stomatitis.

Keywords

Denture stomatitis, Candida albicans, clotrimazole, chlorhexidine digluconate