Abstracts of Students for 3rd Research Methodology Workshop for Undergraduates (RMWU) held at Gian Sagar Medical College & Hospital on 23rd August, 2014
Adverse drug reactions (ADRs) to skin are common; however information about their incidence, severity is scanty. The aim of the present study was to detect, assess and report suspected ADRs in Department of Dermatology, SGRDIMSAR, Amritsar so as to treat and stop indiscriminate use of drugs in clinical practice.
A prospective study was undertaken in patients presenting with ADR in Dermatology OPD of SGRDIMSAR, Amritsar which is a tertiary care hospital in Punjab. The study period was from July 2013 to June 2014. A suitable statistical test was applied for analysis of data.
A total of 78 ADRs were detected, documented, assessed and reported during the study period. Assessment of severity of the suspected ADRs revealed that 12% of suspected ADRs were severe, 49% were moderate and rests were of mild intensity. Most of the ADRs were from NSAIDs followed by fluoroquinoloes, antitubercular, antiepileptic agents and others. The most common type of ADR was urticaria followed by fixed drug eruptions, maculopapular rash and others. Causality assessment revealed that 63% of ADRs were possibly drug related. Preventability of ADRs was assessed which revealed that 61% of ADRs were preventable.
Thus to conclude the study indicate that pharmacovigilance activity is significantly effective in increasing the reporting of ADRS.
