Haemato-biochemical impact of primary infection of Oesophagostomum columbianum in goat

An experiment was carried out to study the haemato-biochemical impact of primary infection of Oesophagostomum columbianum infection in goat. Thirteen Black Bengal goats of either sexes, 30-45-day-old, were maintained following standard practices up to five months of age for use in the experimental establishment of O. columbianum infection. Out of thirteen goats, two were used as donor animals and rests eleven were divided into two groups i.e. infected group (n=6) and control group (n=5). Infected group of goats were drenched with L₃ of O. columbianum @ 600 L₃/kg. body weight. Per-rectal faecal sample from infected goats were collected from 41 DPI at weekly interval till 8^th week of patency to determine faecal egg out put. Blood samples were collected from all the experimental goats once before giving the infection and on three occasions at 14 days intervals following the appearance of Oesophagostomum eggs in the faeces of infected goats. O. columbianum infection had significant (p<0.01) impact on haematological parameters with decreased value of Hb, PCV, TEC and TLC in the infected goats. O. columbianum infection resulted hyperglobulinaemia and hypoprotinaemia with significantly (p<0.01) decreased value of total serum protein and serum albumin in infected goats. Serum iron concentration decreased significantly (p<0.05) in infected goats compared to control goats.