Comparative haemato-biochemical response to orally administered anthelmintics namely generic ivermectin/oxfendazole in bolus formulation, and Nigella sativa ‘kalajira’, and Caesalpinea crista ‘gatran’ crude seed powder in countering the deleterious in vivo effects of GI nematodiasis in lactating indigenous cows was evaluated. The hemoglobin (Hb) concentration, packed cell volume (PCV%) and total erythrocyte count (TEC) remained significantly reduced in the early post-treatment period concurrent with marked leucocytosis. However, a significant improvement, especially with ivermectin or oxfendazole, clinically manifested by restoration of near normal values, was observed towards the end of the trial i.e. by 28 day. The circulatory levels of total protein, albumin and globulin fractions, and glucose revealed a perceptible early declining trend but, in general, the values were restored to near normal by day 28. The favorable therapeutic response with ivermectin/oxfendazole was relatively faster.
Haemato-biochemical profile, Nematodiasis, Cow, Therapy
