Anthelmintic therapy and haemato-biochemical response in dogs with ancylostomosis

A study was conducted to find out the anthelmintic efficacy of ivermectin and pyrantel pamoate based on single dose administration @ 0.2mg/kg s/c and 5mg/kg per os respectively, in dogs with ancylostomosis. The dogs presented in the Teaching Veterinary Clinical Complex of Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana were divided into four groups, Group I (Healthy control), Group II (placebo control), Group III (treated with ivermectin) and Group IV (treated with pyrantel pamoate). Quantification of eggs per gram (EPG) of faeces on 0, 7^th and 15^th day post-treatment (DPT) revealed that the efficacy was 100% following treatment with ivermectin and pyrantel pamoate on 7^th DPT on reduction in EPG. The study revealed decrease in Hb, packed cell volume (PCV), total erythrocyte count (TEC), eosinophilia, hypoalbuminaemia, hypoproteinaemia and decreased serum iron in Ancylostoma infected dogs. Improvement in haemato-biochemical parameters was observed following treatment.