Journal Of Veterinary Pharmacology And Toxicology
  • Year: 2018
  • Volume: 17
  • Issue: 2

Safety evaluation of oleic acid in isoprenaline induced myocardial injured rats

  • Author:
  • Pawan Kumar Singh, Manjugari, Jagadeesht, Vandanasingh, Amit Shukla, Soumen Choudhury, Satish K Garg
  • Total Page Count: 3
  • Page Number: 67 to 69

Department of Veterinary Pharmacology and Toxicology, College of Veterinary Sciences and Animal Husbandry Uttar PradeshPandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura, 281001

* Corresponding author e-mail: chsoumenpharma@gmail.com

Online published on 8 April, 2021.

Abstract

The lifestyle diseases have emerged as a naive threat to the human beings and to curtail the incidence and emergence of these disorders such as cardiovascular disorders and other diseases; the use of several agents has been advocated. Oleic acid has role as anti-inflammatory and antioxidant. Therefore, present study was conducted to ascertain the safety haematological and analytic profile of oleic acid treatment in myocardial infarction cases in rats. The study showed no significant alteration in hematogram and also revealed the presence of oleic acid in cardiac tissue as retention time by GC-MS found to be around 41.9 min. Thus, study confers the utility of oleic acid in the cases of myocardial infarction and other cardiovascular diseases.

Keywords

Isoprenaline, Myocardial infarction, Oleic acid, Gc-MS