Hepatoprotective effect of Amaranthus Hypochondriacus on arsenic intoxicicated wlh cockerels

The hepatoprotective effect of seed powder of Amaranthus hypochondriacus (SPAH) were evaluated in arsenic treated WLH cockerels. Thirty WLH cockerels were randomly divided into five groups of six birds each. Group I served as control. Group II was administered arsenic @110 ppm as a standard toxicant drug. Group III was administered SPAH @ 8000 ppm and groups IV and V were given arsenic@110ppm + silymarin@100ppm and arsenic @110ppm+SPAH@8000ppm, respectively, for 60 days. Results showed that arsenic -induced an elevation of alanine aminotransferase (ALT), aspartate amino transferase (AST), alkaline phosphatase (ALP) and gamma glutamyl transferase (GGT) levels which were significantly(P<0.05) reduced by simultaneous treatment with SPAH with an increase in body weight. It is concluded from this study that SPAH revealed a protective effect against arsenic induced hepatic damage in WLH cockerels.