Journal Of Veterinary Pharmacology And Toxicology
  • Year: 2022
  • Volume: 21
  • Issue: 1

Ameliorative efficacy of Amaranthus hypochondriacus against arsenic induced haemotoxicity in WLH cockerels

  • Author:
  • Renuka Aswal*, S. P. Singh, Deeksha Maletha, Dinesh Pandey1
  • Total Page Count: 3
  • Page Number: 69 to 71

1MBGE, CBSHGBPUAT, Pantnagar-263145, U.S. Nagar, Uttarakhand

Department of Veterinary Pharmacology and Toxicology, C VA Sc., GBPUAT, Pantnagar-263145, U.S. Nagar, Uttarakhand

*Corresponding author Email-renukaaswal@gmail.com

Online Published on 24 November, 2022.

Abstract

The aim of this study was to evaluate the ameliorative efficacy of Amaranthus hypochondriacus seeds against arsenic intoxication in WLH cockerels.Thirty WLH cockerels were equally and randomly divided into 5 groups with 6 birds in each group. Group I served as control; group II was given arsenic@110ppm in feed; group III were given seed powder of Amaranthus hypochondriacus (SPAH) @8000ppm in feed; group IV arsenic @110ppm along with silymarin@100ppm in feed and group V given arsenic @110ppm alongwith seed powder of Amaranthus hypochondriacus (SPAH) @8000ppm in feed. The study was conducted for 60 days and the blood samples were collected at 30th and 60th day for analyzing the hematological profile. Arsenic caused significant (P<0.5) reduction in hemoglobin (Hb), packed cell volume (PCV), total erythrocyte count (TEC) and total leukocyte count (TLC) as compared to control group I. Amaranth alone in group III was at par with control group I and revealed potentiating effect on haematological parameters suggesting the protective effect of Amaranthus hypochondriacus against arsenic induced hemotoxicity. It is concluded from this study that Amaranthus hypochondriacus @ 8000 ppm in feed showed ameliorative efficacy against arsenic intoxication in a 60 days study WLH cockerels.

Keywords

Amaranthus hypochondriacus, Arsenic, Intoxication, Hemotoxic, WLH cockerels