1Associate Professor, Department of Veterinary Pharmacology & Toxicology, Bihar Veterinary College, Bihar Animal Science University, Patna-800014
2Department of Veterinary Physiology, Bihar Veterinary College, Bihar Animal Science University, Patna-800014
3Assistant Professor, College of Agriculture, Bihar Agriculture College, Sabour, Bhagalpur, Bihar
4Professor & Dean, Department of Pharmacology & Toxicology, College of Veterinary and Animal Sciences, G.B. Pant University of Agriculture and Technology, Pantnagar, 263145
*Corresponding author's e-mail: drgovindvet2003@gmail.com
Online published on 28 November, 2023.
Reactive oxygen and nitrogen species (RONS) are essential signaling molecules in various physiological processes, but their excessive production can lead to oxidative stress which are responsible for numerous diseases. Antioxidant systems counteract the detrimental effects of RONS, maintaining cellular homeostasis. This review delves into the intricate interplay between RONS and antioxidants. RONS, including superoxide radicals, hydrogen peroxide, hydroxyl radicals and nitric oxide, are generated as natural byproducts of cellular metabolism, immune responses, and environmental exposures. Exploring the intricacies of these systems could open the door to creative ways of using RONS for medical advantages by reducing their harmful impacts.
Antioxidant, Exogenous source of oxidants, Hyperoxia, Ionizing radiation, RONS
