Lucknow Journal of Science
  • Year: 2007
  • Volume: 4
  • Issue: 2

Antimicrobial study of 3-(5-Methyl[4,5]Imidazo/Benzo [4,5] Imidazo[1,2a]Quinolin-2-Yl-Oxy)-1-Phenyl-3-Aryl-Propan-1-Ones

  • Author:
  • V.K. Pandey, Saurabh Singh, Neelam Sharma, Ridam Misra
  • Total Page Count: 6
  • Page Number: 21 to 26

*Department of Chemistry, University of Lucknow, Lucknow - 226007.

Abstract

Reaction of resorcinol with ethylacetoacetate (EAA) in presence of concentrated sulphuric acid afforded 7-Hydroxy-4-methyl-chromen-2-one 1 which on reaction with o-phenylene diamine/ethylene diamine in dry pyridine resulted in 5-Methyl[4,5]imidazo/benzo[4,5]imidazo[1,2a]quinolin-2-ol 2. When 2 was reacted with α, β unsaturated carbonyl compounds in dioxane and triethylamine 3-(5-Methyl[4,5] imidazo/benzo[4,5]imidazo[1,2a] quinolin-2-yl-oxy)-1-phenyl 3-aryl-propan-1-ones 3 were obtained. Compounds 3 were examined for their antimicrobial and antiviral activities.