1Division of Toxicology, Central Drug Research Institute, Chattar Manzil Palace, Lucknow-226001, U.P., India.
2Department of Chemistry, D.A.V.P.G. College, C.S.J.M. University, Kanpur, U.P., India.
3Department of Biotechnology, I.I.L.M. Academy for Higher Learning, Greater Noida, U.P., India.
SMA has also been used for the preparation of chemically and diffusionaly controled polymeric prodrug. Poly (Styreneco-maleic anhydride) conjugates with phenol containing medicinal compounds like 2-methoxy-4-(2-propenyl) Phenol and O-Hydroxy benzoic acid etc. in acetone and dioxane to form derivatives of SMA. The synthesis and hydrolytic behavior of the derivatives in water was studied, and effect of temperature was also measured.
Phenolic medicine, Styrene maleic anhydride
