LS- International Journal of Life Sciences

  • Year: 2014
  • Volume: 3
  • Issue: 1

Antibacterial Activity and Phytochemical Screening of Ocimum sanctum Linn. (Leaves)

  • Author:
  • M. Punithavathi1,, J. Aranganathan2, M. Janani3,
  • Total Page Count: 3
  • Published Online: Apr 1, 2014
  • Page Number: 28 to 30

1Assistant Professor, Department of Biochemistry, Marudhar Kesari Jain College for Women, Vaniyambadi-635 751, Vellore District, Tamil Nadu, India.

2Research Scholar, Department of Biochemistry, Periyar University, Salem-636 011, Tamil Nadu, India.

3Assistant Professor, Department of Biochemistry, Auxilium College (Autonomous), Vellore-632 006, Tamil Nadu, India.

Abstract

The antibacterial effect of the leaves of Ocium sanctum Linn (Lamiaceae) was evaluated on bacterial strains like Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Salmonella typhi and Vibrio chol-erae. The in vitro antibacterial activity was studied by agar cup method and compared with the standard antibiotic, streptomycin (1000 µg). Maximum activity was exhibited by ethanolic leaves extract against B. subtilus and V. cholerae. S. aureus, Salmonella typhi and E. coli exhibited minimum activity. The different solvent extracts showed the presence of secondary metabolites like tannin, saponin, flavonoids, alkaloids, proteins and steroids. The results obtained in the present study suggest that O. sanctum Linn can be used in treating diseases caused by the test organisms.

Keywords

Antibacterial, Bacillus subtilus, Ocimum sanctum, Pathogen, Streptomycin