Structure Prediction and Structural Aspects of Hypothetical Proteins of Human Papilloma Virus (HPV)

Human papillomavirus (HPV) is mostly linked to cervical cancer among women. The genome analysis of HPV has revealed the presence of multiple hypothetical proteins whose functions are unknown. In this study, we have used bioinformatics tools, such as National Center for Biotechnology Information-Basic Local Alignment Search Tool, INTERPROSCAN, PFAM and Clusters of Orthologous Groups, for the prediction of functional conserved domains in the hypothetical proteins. The functional domain and structure prediction of these uncharacterised proteins may be helpful in using them as future drug targets by establishing their existence in the metabolic pathways of HPV.