Antibacterial Studies of Rhizophora mucronata with Special Reference to Staphylococcus aureus Isolated from Diabetic Foot Ulcer Patients

The plant was selected for experimental studies, based on the importance of medicinally value (ethno botanical identification) and taxonomical identification. The Staphylococcusaureus was isolated from diabetic foot ulcer patients in aseptic condition. The isolated organisms were identified based on morphological characteristics. For screening of antibacterial activity of Rhizophoramucronata leaves were collected from Pichavaram and washed, shade-dried and powdered for methanol extract preparation by using Soxhlet apparatus. Antibacterial assay was studied against S. aureus by disc diffusion method (Kirby–Bayer method). The methanol extracts of R. mucronata showed maximum inhibition zone of 14 mm and the lowest inhibition zone of 10 mm was recorded. The preliminary phytochemical analysis of R. mucronata using methanol extract has potential activity. Alkaloids, terpenoids, steroids, tannins, quinones, saponins, flavonoids and phenols were present in methanol extract of R. mucronata. Therefore, the phytoconstituents in R. mucronata provides that they are effective and can lead to the development of drug for diabetic foot ulcer. It can be hoped that the R. mucronata will provide the most valuable drugs against wound infection.