Mangalmay Journal of Management & Technology
  • Year: 2017
  • Volume: 7
  • Issue: 2

Spectral and biological evaluation of 5-Methyl-1, 3, 4-Thiadiazol-2-Amine

  • Author:
  • Rovin1, Dharmendra Kumar2, Leeladhar Singh3, Vikas Kumar4
  • Total Page Count: 8
  • Page Number: 452 to 459

1Research Scholar Monad University, Ghaziabad

2Associate Professor, IIMT Engineering College, Meerut

3Research Scholar, Monad University, Ghaziabad

4Assistant Professor, IIMT Engineering College, Meerut

Online published on 15 February, 2019.

Abstract

In the current study, a compound 5-Methyl-1, 3, 4-thiadiazol-2-amine was synthesized by reaction thiosemicarbazide, acetic acid and hydrochloric acid. The structure of the synthesized compound was confirmed based on 1H-NMR, IR, UV-Vis and mass spectral data. The synthesized compounds were screened for antimicrobial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus and fungus Candida albican, Aspergillus niger and Candida krusei.

Keywords

FTIR, NMR, Raman spectroscopy, UV-Visible spectroscopy, Thiadiazole, antimicrobial activity