1Department of Pharmacology Navodaya Medical College, Raichur, Karnataka
2Departmtment of Pharmacology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha
3Department of Forensic Medicine, S.S.Institute of Medical Sciences & Research Centre Davangere-577005, Karnataka. India
4Department of Microbiology Navodaya Medical College Raichur Karnataka, India
Online published on 24 February, 2012.
To evaluate antiinflammatory activity of 70% alcoholic extract of neem root.
The 70% of alcoholic extract of neem root(NRE)was given in the dose of 200,400,800 mg/kg in wistar albino rats of either sex in test group and for comparison Aspirin was given in the dose of 100 mg/kg in standard group. These animals were tested in carrageenan induced rat paw edema(for 24 hours) and cotton pellet granuloma(7 days)
NRE in the dose of 800 mg/kg showed significant (p<0.05)in carrageenan induced rat paw edema model.NRE in the dose of 400 and 800 mg/kg showed significant (P<0.05 and p<0.01) in cotton pellet granuloma.But in both models it was less significant than Aspirin
NRE has antiinflammatory activity.
Neem root, Alcohol, Anti-inflammatory effect
