Medico-Legal Update
  • Year: 2012
  • Volume: 12
  • Issue: 2

Significance of Serum Cholinesterase Level in Organophosphate Poisoning

  • Author:
  • H. G. Kukde1, V.N. Ambade2, A.K. Batra3, A.N. Keoliya4
  • Total Page Count: 5
  • Page Number: 70 to 74

1Assistant Professor, Department of Forensic Medicine, Lokmanya Tilak Municipal Medical College & General Hospital, Sion, Mumbai

2Associate Professor, Department of Forensic Medicine, Government Medical College, Nagpur

3Associate Professor, Department of Forensic Medicine, Shri Vasantrao Naik Government Medical College, Yavatmal

4Professor & Head, Department of Forensic Medicine, Indira Gandhi Government Medical College, Nagpur

Online published on 17 November, 2012.

Abstract

Consumption of Organophosphorus compound is one of the commonest modes of committing suicide in rural India. This study was conducted with aim to correlate the serum cholinesterase level and severity of organophosphorus poisoning. Estimation of serum cholinesterase levels are widely used to measure the esterases which clear acetyl choline. Calorimetric procedure of Ellman as described by Venkatraman was used to measure the acetyl cholinesterase activity in patient admitted at Vasantrao Naik Government Medical College, Yavatmal with clear diagnosis of organophosphorus poisoning and postmortem cases autopsied at mortury of Vasantrao Naik Government Medical College, Yavatmal.

Keywords

Poisoning, Organophosphate Compound, Serum Cholinesterase Level, Calorimetric