1Professor, Department of Oral & Maxillofacial Pathology, MM College of Dental Sciences & Research, Mullana, Ambala, Haryana, India
2Department of Oral Pathology, Aditya Dental College, Beed, Maharashtra
3Department of Pediatric Dentistry, MAHS A university, Kualalumpur, Malaysia
4Department of Pedodontics and Preventive Dentistry, College of Dental Science, Amargadh, Bhavnagar, Gujarat
5Department of Oral Pathology, Surendera Dental College and Research Institute, Sri Ganganagr, Rajasthan, India
6Department of Conservative and Endodontics, National Dental College, Derra Bassi, Punjab, India
Online published on 20 February, 2014.
Malignant melanoma is a neoplasm of melanocytic origin that arises from a benign melanocytic lesion or denovo from melanocytes within otherwise normal skin or mucosa. Primary malignant melanoma of the oral cavity is a rare neoplasm and is considered among the most deadly of all human neoplasms. This malignancy commonly affects male subjects and the average age for diagnosis of oral melanoma is 55 years. A biopsy is required to establish a diagnosis. Ablative surgery with tumor-free margins remains the treatment of choice. Described is a case of malignant melanoma of the maxillary gingiva in a 42-year-old female. Immunohistochemistry using HMB-45 and S100 was done for confirmatory diagnosis.
HMB-45, Maxillary Gingiva, Melanoma, Malignant, Oral Melanoma, S100