Anatomical Variation of Left Anterior Descending Artery and Atherosclerotic Coronary Artery Disease in Sudden Cardiac Death

Evaluation of sudden cardiac death below 40 years of age, due to atherosclerotic coronary artery disease involving left coronary artery revealed a branching of the Proximal part of left anterior descending artery. There was an age dependent preponderance of atherosclerosis at this branching site. Hence a series of death due to Coronary artery disease below the age of 40 years were analysed which revealed the branching of proximal left anterior descending artery. Branching of proximal left anterior descending artery, an anatomical variation of coronary artery predisposes early atherosclerosis of the proximal left anterior descending artery resulting in death at a younger age compared to people with single non-branching left anterior descending artery.