Medicinal Plants - International Journal of Phytomedicines and Related Industries
SCOPUS
  • Year: 2009
  • Volume: 1
  • Issue: 2

Free radical scavenging activity of Capparis zeylanica

1R.C. Patel College of Pharmacy, Shirpur, Maharashtra - 425 405, India.

2JZMD Society's College of Pharmacy, Mamurabad, Dist - Jalgaon, Maharashtra - 425 404, India.

*Corresponding author: Surendra S. Agrawal, E-mail: surendra_pharma@rediffmail.com

Abstract

In the present study in vitro antioxidant potentiality of the fractions obtained from the methanolic extract of aerial part of Capparis zeylanica by 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) method and scavenging of superoxide anion radical-generated non-enzymatic system was studied. The Ethyl acetate (EF) and n-Butanol (BF) fractions had showed promising free radical scavenging effect of DPPH and free radical scavenging action against nitric oxide (NO) induced release of free radicals at the concentration 100 μg/ml. The BF showed more scavenging activity than other fractions, comparable to ascorbic acid (Reference Standard). Further studies may explore a potential free radical scavenger from the Capparis zeylanica.

Keywords

Antioxidant, Capparis zeylanica, DPPH, Nitric oxide scavenging