Hepato and Nephroprotective effects of six important medicinal plants against toxic oxidative stress

In the current scenario, consumption of adulterated food, junk food, excessive usage of allopathic medicines, exposure to toxic chemicals and sedentary lifestyle are the primary reasons for the failure of liver and kidney due to oxidative stress. Ayurveda, Indian traditional medicine is becoming popular in view of its safety, no side effects and low cost. Therefore, plant-based medical research has increased all over the world. The plant therapy reduces the oxidative stress in the liver and kidney of experimental animals, the stress induced by toxic chemicals. The supplement of plant extracts either in single or in a combination of various herbal extracts improves the activity of the antioxidative enzymes, reduces the stress markers, normalizes the biochemical parameters and the liver and kidney function. The hepato and nephroprotective ethno-pharmacological activities of six medicinal plants like Phyllanthus niruri, Solanum xanthocarpum, polyalthia cerasoides, Acalypha indica, Tinospora cordifolia and Nigella sativa are discussed in the paper.