Medicinal Plants - International Journal of Phytomedicines and Related Industries
SCOPUS
  • Year: 2010
  • Volume: 2
  • Issue: 3

Antifungal activity of a new steroid isolated from Abutilon indicum (L.) Sw.

  • Author:
  • S.K. Prabhuji1,, Deepak Kumar Singh2, Atul Kumar Srivastava3, Rahul Sinha2
  • Total Page Count: 4
  • Page Number: 215 to 218

1Biotechnology and Molecular Biology Centre, M.G. Post Graduate College, Gorakhpur-273001, UP, India

2Deptt. of Chemistry, D.D.U. Gorakhpur University, Gorakhpur-273009, UP, India

3Deptt. of Chemistry, M.G. Post Graduate College, Gorakhpur-273001, UP, India

*Corresponding author : S.K. Prabhuji, E-mail : shaktiprabhuji@rediffmail.com.

Abstract

A new steroidal compound 20, 23-dimethylcholesta-6, 22-dien-3β-ol has been isolated from the stem tissues of Abutilon indicum. The structure of the compound was elucidated by spectral and chemical studies. The compound was found to be 100% effective at 5000 ppm in controlling the mycelial growth of Aspergillus parasiticus var. globosus and Aspergillus terreus var. aureus using the poison food technique. For other fungi like Aspergillus flavus, A. versicolor and A. fischeri, it was fungistatic.

Keywords

Abutilon indicum, 20, 23-dimethylcholesta-6, 22-dien-3β-ol, new steroid, antifungal activity