1Department of Plant Molecular Biology, MRD Life Sciences, Lucknow-226010, U.P., India
2Department of Biotechnology, Bundelkhand University, Jhansi, U.P., India
*Corresponding author: Ram Prakash Mishra, e-mail : mail@rpmishra.com; rpmishra@mrdlifesciences.com
Online published on 27 January, 2012.
Anthocephalus cadamba is ethnomedically widely used in the form of paste by tribe in Western Ghats for treating skin diseases. In this context, antifungal properties of Anthocephalus cadamba against a wide range of pathogens were studied. The alcoholic and aqueous extracts of fruits (ripened and un-ripened) showed significant antifungal activity against Trichophyton rubrum, Candida albicans, Microsporum species, Aspergillus niger, with zone of inhibition of the maximum 15.0 mm and 12.0 mm against Trichophyton rubrum for ethanolic and hot water extracts, respectively. The MIC was as low as 2.00 mg/ml and 2.5 mg/ml for ethanolic and methanolic extracts of ripened fruit of A. cadamba against Trichophyton rubrum and Aspergillus niger, respectively.
Anthocephalus cadamba, Antifungal properties, Trichophyton rubrum, Candida albicans, Microsporum, Aspergillus niger
