Production of a new mixed herbal medicine for minor Aphthous Ulcers

Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosa lesions seen in primary care. RAS is a pathologic condition characterized by recurring, painful, small oral mucosal ulcers with a round or oval aspect, clean borders. The aim of this study was to recognize the effect of a new mixed herbal medicine on minor RAS as a treatment, which is more effective and has fewer side effects. This study was done by double blind method. 38 patients without any systematic illness were investigated in two groups: case group (19 patients) and blank treatment (19 patients). A new mixed herbal medicine was used for both the groups. This medicine includes Rosa damascena, Melissa officinalis, Quercus robur and Portulaca olearaceae. The results showed an effective treatment for minor aphthous ulcers through using the four herbal products which showed a shorter healing period with fewer side effects.