Department of Bioenergy, School of Energy, Environment and Natural Resources, Madurai Kamaraj University, Madurai – 625 021, Tamil Nadu, India
Online published on 12 November, 2012.
The present study was aimed to analyse active compounds by GC-MS analysis, and investigate the cytotoxic and phytotoxic activity of Tabebuia rosea (Bertol.) DC flower extract. The cytotoxic activity of flower extract was evaluated by brine shrimp lethality bioassay method and the LC50 value found to be 46.93 μg/ml compared to taxol 0.85 μg/ml. Phytotoxicity assay showed significant root length inhibition by the extract at the concentrations of 100 ppm, 1000 ppm and 10000 ppm. Similarly, seed germination studies showed that the flower extracts possess significant inhibition at the concentrations 1000 ppm and 7500 ppm. Thus the cytotoxic and phytotoxic activity of the flower extract can be attributed due to the presence of 4H- Pyran-4 –one, 2, 3- Dihydro-3, 5- dihydroxy-6- methyl, 3, 4, 5-trimethyl phenol, thiocyanic acid, 2-propynyl ester and 2-propenoic acid, 3-(2-hydroxy phenol) compounds in the extract.
Tabebuia rosea, GC-MS analysis, cytotoxicity, phytotoxicity, radish seed, Artemia salina, 3,4,5-trimethyl phenol, 4H-Pyran-4-one, 2,3-Dihydro-3, 5-dihydroxy-6-methyl
