Medicinal Plants - International Journal of Phytomedicines and Related Industries
SCOPUS
  • Year: 2014
  • Volume: 6
  • Issue: 1

Variation in bioactive content in Andrographis paniculata nees at different growth stages

  • Author:
  • Arunkumar Phurailtapam1,, Aarti Kawane2, Satyabrata Maiti2, Gaur Gopal Maiti3
  • Total Page Count: 9
  • Page Number: 53 to 61

1College of Horticulture and Forestry, Central Agricultural University, Pasighat, Arunachal Pradesh, India

2Directorate of Medicinal and Aromatic Plants Research, Anand, 387310, Gujarat, India

3Kalyani University, Kalyani, 741235, Nadia, West Bengal, India

*Corresponding author: Arunkumar Phurailatpam, e-mail: arunkumarph@gmail.com

Online published on 18 April, 2014.

Abstract

An investigation was carried out to study the effect of plant age on different morphological characters and the corresponding changes in the bioactive compound (andrographolide) in the three accessions of Andrographis paniculata. The results have shown significant differences and changes in the andrographolide content and yield at various growth stages of the plant. The three accessions with no morphological differences were characterized using RAPD and ISSR profiles and the variation in andrographolide content was estimated by HPLC. A plant age of 80–105 DAT (days after transplantation) may be recommended for harvesting to get a good andrographolide yield though the highest herbage yield may be obtained at 120 DAT.

Keywords

Andrographis, Andrographolide, Date of harvesting, HPLC, RAPD