1Professor and HOD, Department of Psychiatry, Tezpur Medical College Hospital, Tezpur, Assam, India
2RMO cum Clinical Tutor, Department of Psychiatry, Rampurhat Govt. Medical College and Hospital, Rampurhat, West Bengal, India
*Correspondence: Dr. Sandipan Nayek, Jagatberh (Kalachandtala), P.O. Sripally, Purba Bardhaman, PIN-713103, West Bengal, India. sandipannayek@gmail.com
Online published on 28 June, 2019.
Levosulpiride is chemically a substituted benzamide which acts as an atypical antipsychotic and prokinetic agent. There is dearth of study and limited research on levosulpiride-induced tardive dyskinesia (TD) and its abuse potential till date. Levosulpiride can cause TD which is related to an apparent dopaminergic hyperactivity after long-term blockade of presynaptic dopaminergic D2 receptors. So, detailed drug history should be taken to detect the rare cases of levosulpiride-induced TD and physicians should be cautious in using levosulpiride, particularly in elderly patients.
Benzamide, Antipsychotic, Prokinetic, Dopamine, Elderly
