Autism: epileptiform discharge in EEG with and without seizure disorder

Autism, also known as autistic spectrum disorder, is a neurodevelopmental disorder, characterised by social and communication deficit with repetitive behaviour and restrictive interest. Epilepsy has been found to be highly comorbid disorder though range varies. But epileptiform discharge in autism without history of epilepsy has been reported by various studies. There is no treatment recommendation for abnormal EEG without history of clinical seizure with anticonvulsant in these populations due to the lack of controlled trials. These abnormal EEG may have an important role to explore its association with autism.