1Adult and Forensic Psychiatrist, Clinic for Psychiatric Disorders, "Dr Laza Lazarevic", Belgrade, Serbia
2Psychiatrist, Clinic for Psychiatric Disorders, "Dr Laza Lazarevic", Belgrade, Serbia
3Head of Clinic for Psychiatric Disorders, "Dr Laza Lazarevic", Belgrade, Serbia and Full Professor and Chairman of Psychiatry Department, Faculty of Medicine, Kragujevac, Serbia
4Full Professor of Neurology, Faculty for Special Education and Rehabilitation, University of Belgrade, Belgrade, Serbia
5Full Professor of Pharmacology, Faculty of Medical Sciences, Kragujevac, Serbia
*Correspondence: Ivana Stasevic Karlicic, Clinic for Psychiatric Disorders, "Dr Laza Lazarevic", Visegradska 26, 11000 Belgrade, Serbia. ivanastasevic73@gmail.com
Online published on 1 July, 2016.
Neuroleptic malignant syndrome (NMS) is a life-threatening, often fatal idiosyncratic reaction to neuroleptic or other drug therapies that antagonise the central dopaminergic neurotransmission. The clinical presentation of NMS is very heterogeneous. The lack of specific levels of symptom severity in currently used diagnostic criteria dims the diagnosis of NMS. Therefore differential diagnosis is of priority, because NMS is a diagnosis of exclusion. The aim of this paper is to present a complex clinical picture in a patient that after a differential diagnostic exclusion of other medical conditions and intoxications is diagnosed as NMS. Case reports such as these help raise awareness of this clinical issue.
Antipsychotic Agents, Dopamine, Anti-N-Methyl-D-Aspartate Receptor Encephalitis
