Open Journal of Psychiatry & Allied Sciences
Open Access
  • Year: 2017
  • Volume: 8
  • Issue: 1

Acute dystonia with concomitant use of amitriptyline and paroxetine

1Assistant Professor, Department of Psychiatry, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India

2Resident, Department of Psychiatry, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India

3Associate Professor, Department of Psychiatry, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India

*Correspondence: Dr. Sachin Ratan Gedam, MD, Assistant Professor, Department of Psychiatry, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha-442005, Maharashtra, India. sachinrgedam@gmail.com

Online published on 2 January, 2017.

Abstract

Amitriptyline and paroxetine are antidepressant agents useful for the treatment depressive disorders. Antidepressant induced extrapyramidal symptoms represent an under recognised but important clinical entity as it can adversely impact treatment adherence. Cases of acute dystonia have been reported with selective serotonin reuptake inhibitors but there are only few cases reporting dystonia on amitriptyline. To add to this literature, we report a case of middle aged female who developed dystonia on amitriptyline while already being treated with paroxetine. So, it is warranted to be aware of combination therapy's side effects.

Keywords

Antidepressive Agents, Depressive Disorder, Extrapyramidal Symptoms, Serotonin Uptake Inhibitors