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Natural products either as standardized plant extracts provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Forty extracts obtained from the leaves, stem, rachis, megasporophyll, cone and seed of seven plant species representing four gymnosperm families have been screened for their anti-bacterial activity. T. orientalis, Taxus sp., P. roxburghii, C. revoluta and Taxodium sp. in particular exhibited significant antibacterial activity. The crude extract and hexane fraction of leaves of Taxodium sp. exhibited a significantly specific activity against the staphylococci.